Best Hospital Grade Whole House Air Purifier – A COMPLETE Guide

Where room air purifiers which are used to purify the air in individual spaces, whole-house air purifiers are installed at the inlet of existing heating, ventilation, and air conditioning (HVAC) systems to provide fresh air inside your whole home at one time.

In this article, we have shortlisted 6 hospital grade whole house air purifiers, including three portable and three in duct units, to give you the flexibility to choose the one that best matches your requirements!

Without further due, let’s dive deep into it.

OVERALL BEST HOSPITAL GRADE WHOLE HOUSE AIR PURIFIER:

#1 IQAir HealthPro Plus Medical-Grade Air Purifier

The arrangement of the filters are as follows:

PreMax Pre-Filter > Fan > V5-Cell (Activated Carbon & Aluminum) > HyperHEPA H13 True HEPA Filter

IQAir operates with an advanced micro-fiber filtration technology, which filters particles 100x thinner than ordinary HEPA filters used in traditional air purifiers. Thanks to their ultra-fine threads, the medical-grade HyperHEPA is extremely effective in barricading air contaminants.

MERV is the abbreviation for the Minimum Efficiency Reporting Value, and this system was created by ASHRAE to analyze how efficient the filtration system is in cleaning the air. Its lowest value is 1, and the highest rating is 16.

The IQAir HealthPro Plus is the only product on this list that has got the MERV 16 rating, which is the highest rating in the domain of home air cleaning by the removal of mold spores, bacteria, pollen, viruses, dust, and other harmful contaminants which are injurious to health.

The purifier unit is designed for a massive 1125 ft² with 5 air changes per hour, and IQAir claims that its whole-house air purifier is able to trap at least 99.5% of all particles, which is magnificent.

This makes the IQAir HealthPro Plus perfect for both large and small spaces.

Being the industry standard, it's unsurprising that even the US Olympic Team used the IQAir HealthPro Plus in their athlete housing and training centers! 

It has a very quiet operation as it doesn’t have any moving parts. Thanks to its innovative design, its newly updated fan is suspended with eight incorporated shock absorbers which emits a noise level of 25-59 decibels.

This unit provides another added advantage: it consumes less power - 27 Watts at the lowest speed - meaning you save on cost while passing and cleaning more air at one time. 

Most filters act as a resistance against the flow that puts the load on your purifier. This isn’t the case with IQAir HealthPro Plus. 

From our experience, if you intend to use this unit for 24 hours a day 7 days a week, its filter will still last one and a half years! By reducing the usage by ~50%, you can prolong its filter life up to more than 4 years.

This air purifier is also backed by the prestigious Seal of Approval from the Parent Tested/Parent Approved (PTPA) making it perfect for people suffering from Asthma and other allergies.

With the exemption of filter replacements, IQAir provides 10 years of limited warranty on its HealthPro Plus whole house air purifier, which builds the confidence of buyers on this unit.  

Other Great Hospital Grade Whole House Air Purifiers (Honorable Mentions)

#2 Medify MA-40W V2.0 Air Purifier

The medical grade H13 HEPA filter is very handy in removing even very thin pollutants up to the size of 0.1 microns. Its integration in the purifier enhances the effectiveness of the air purification process.

Three other filtration stages further nullify the chances of bacteria escaping through the purifier while air is purified. So, you’ll get germ free air in your house.

The arrangement of the three filters along with the ionizer is as follows:

Pre-Filter > H13 True HEPA Filter > Activated Carbon Filter > Ionizer

This unit operates at multiple fan speed settings, and its air quality sensor automatically controls the fan speed according to the environment.

This unit can recirculate the air once per hour in an area of 1,600 ft². It will be twice in a room of 840 ft^2, and similarly, you can estimate this value according to your room area.

Thanks to its programmable timer, you will have the flexibility to automate the air purification process for up to 8 hours.

There is also a night mode which dims all lights and turns off the ionizer for a sound sleep.

Having lifetime warranty along with CARB, Energy Star & ETL certification, this is one the most reliable and trusted hospital grade whole house air purifiers.

CARB certification marks this unit to be ozone-free, making it the perfect purifier to be used in hospitals or for patients at home.

For those that don’t want their naughty children to play with the purifier’s settings., Medify has added a child lock option in this unit to tackle this issue. With this enabled,  your children will unlikely disturb it unknowingly. 

According to the data provided by Medify, the MA-40W Air Purifier produces 66 dB of noise at maximum fan speed, which can be a bit noisy.

In addition, the filters installed in this unit are limited for only 2500 hours, so you’ll need to replace them every six months. Otherwise, Medify may not honor the warranty in case of any failure resulting due to clogged filters.

One thing that you need to keep in mind is that replacement filters take two weeks to reach your home before you order them, so do buy an extra one to deal with in case of any emergency.

#3 Hathaspace HSP001 Air Purifier

The arrangement of the filters and ionizer are as follows:

Cold Catalyst Filter > Activated Carbon Filter > Antibacterial Filter > True HEPA Filter > Ionizer

The Cold Catalyst filter works just like a pre-filter that filters out the large dust particles and mold. The function of other filters is explained in the buyer’s guide section.

This unit can operate on Auto-mode, of which smart sensors measure the air quality in real-time and control the purifier fan speed to ensure hospital grade purification in the room all the time.

This unit can cover the room as big as 700 ft² with one air change per hour and 24 air changes per day. Similarly, in a room of 350 ft², this unit will recirculate the air in half an hour and 48 times in a day.

Thanks to the whisper-quiet technology of this unit, it makes minimal noise during its operation, which is below 45 dB even at maximum fan speed.

By putting the unit on a sleep mode, it’ll dim all lights and will have an operational noise of even less than 20 dB. So, you can place the unit alongside your bed while sleeping.

You’ll get two years of warranty on all of its parts with lifetime customer support, and you can trust this brand as it has a good track record.

Although you can control the purifier settings with the help of remote control, the HathaSpace Air Purifier is not compatible with Alexa. You won’t enjoy the flexibility of mobile app connectivity!

If you are suffering from any lung disease, then this unit would be best for you as it is ozone free and fully approved by the CARB.

HathaSpace suggests replacing the filters every 4-6 months, which you will have to check  manually for overuse as this unit does not have a filter replacement indicator.

Being equipped with all advanced features and having more than 82% 5-star ratings on Amazon, you can trust this unit.

#4 Okaysou AirMax8L Air Purifier

This purifier lets the air pass through 3-Stage Ultra Filtration and 2-Stage Duo filtration and has nearly the same filtration power as HathaSpace Air Purifier.

Filters are arranged in the following manner:

Pre-Filter > HEPA Filter > Antibacterial Filter > Honeycomb Activated Carbon Filter > Cold Catalyst Filter

With the Okaysou Air Purifier, you will have to replace the filters every six months, althoughthe replacement period may vary depending on the usage.

Its replacement filter indicator will notify you when filters need to be changed. But, our recommendation for buying an extra filter beforehand will be very handy.

This purifier unit operates on a Silenceboost technology. Due to its 45 vanes and large motor turbine design, the air enters into the unit from a wider area, which greatly reduces its operational noise.

There is no exact data about the upper limit of the noise level. However, it makes a 22 dB noise while operating at night mode.

This purifier can recirculate air 3 times in an hour, in a 500 ft² room.

With CARB certification, the unit is rated for its ozone-free operation. Apart from that, Okaysou has also got RoHS, CE and ETL certifications listed as well.

You can also lock the settings of the purifier unit by putting the unit on child lock so that your children may not disturb its settings.

The timer function will allow you to automate the purifiers operation for up to 8 hours. In this way, you can save energy as well.

Even with its certifications and advanced features, there are some drawbacks that you’ll have to consider before buying this unit.

One area where this unit lacks is the absence of an air quality sensor. In addition, with no auto-mode, you will have to manually control the fan speed, which isn’t an effective way of purifying the room’s air.

You also won’t enjoy the flexibility of controlling the unit while sitting on your couch. With no remote access, you will have to operate this unit manually.

#5 Clean Comfort In-Duct Air Purifier (UA2000DV)

The UA2000DV use UV lamp technology to kill any kind of germs or bacteria.

It uses two types of UV lights, the first one UV-C germicidal light to kill the viruses, bacteria, and mold while the other one UV-V light deals with chemicals and odors, and transforms them into inactive substances.

To increase the exposure time of air to UV light, a ‘Turbulator’ installed in the purifier unit slows down and spins air containing microbial contaminants in the chamber.

Due to the highly reflective surface of the chamber, the effective intensity of UV light is increased to make the air leaving the chamber germ-free. 

For automatic control, there is a thermistor installed in the unit. However, there isn’t enough information provided by the Clean Comfort about the remote control of this device.

This air purifier unit is specially designed to purify areas of up to 2000 ft². Moreover, this purifier unit doesn’t have too many moving parts, so it operates silently. Thus, operating this unit even during the night won’t disturb you in your sleep.

Its UV lights replacement indicator will be very useful in giving an early heads up!

You will get three years of warranty on all its parts, and due to their responsive customer support, you can expect to get quick assistance while claiming warranty.

We would recommend you not to install this unit on your own. Give this job to a professional to avoid any trouble in the future.

As there are no air filters in this unit, so there won’t be any major maintenance cost. Just replace the light bulbs when required.

This air purifier is also CSA C/US certified, which certification is given to household and gas appliances to ensure that they are risk-free to use.

Overall, this unit is inexpensive and no filter replacement cost is involved in it. However, you may find that the UA2000DV may lose efficiency over time as pollutants tend to get accumulated on the surfaces of UV lamps. In comparison with devices like IQAir, they greatly lose in terms of reliability, efficiency, and performance!

#6 Aprilaire 5000 Electronic Air Purifier

The Aprilaire 5000 is a Ducted, non-portable whole-house air purifier that removes contaminated airborne particles, up to the size of 0.1 microns, by using a combination of electrostatic air cleaning technology and a normal air filter, as claimed by Aprilaire.

The polluted air is allowed to pass through the ionizing wires where  pollutants get charged and collected on the air filtration system due to the electrostatic effect.

The rest of the air  gets purified after passing through the air filter, and goes into the duct where it is distributed into the whole house via your HVAC system.

It perfectly fits into most air ducts, with the rest of the space perfectly sealed to stop contaminated air from getting mixed into the purified air, so you’ll get germ free air being distributed.

This unit has minimal operational noise, and as it is installed in the air duct, you won’t hear any noise. Thus, this silent whole house air purifier won’t disturb you any time during the day or night.

The overall maintenance of this device is quick, and it doesn’t require frequent cleaning. Apart from replacing the air filter twice a year, you’ll just have to wipe the ionizing wires and control electrode once a month.

Installing such a unit prolongs the life of the HVAC duct system as well. With complete absorption of harmful contaminants, there are no chances of corrosion.

This unit can be controlled by the simple to use remote control panel that you can install in any room.

One great feature is that during winters, you can heat up the air passing through the air purifier, and its temperature can be controlled using this control panel.

This panel also shows the temperature of the air entering into the purifier and temperature at which it is exiting the air purifier.

You can also schedule the operation of the purifier unit using the same panel. There are three main air cleaning options of which air purifier can operate.

There is a filter replacement indicator as well on its control panel that gives an early heads up when the filter needs to be changed.

The performance of this purifier unit is tested against ASHRAE 62.2, which is a recognized standard for acceptable indoor air quality and ventilation system design. Needless to say it passes with flying colors.

It is also listed by the UL, which is a global safety certification company that guarantees that this product is safe to use.

You’ll get a limited warranty of five years, which won’t include the replacement of disposable filtration media. But, you should hire a professional to install this unit as it may require some duct modification. Otherwise, you may lose the warranty.

Additionally, in case of any damage to the purifier unit during its installation, Aprilaire won’t entertain you in any way!